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Effect of hemodialysis on short-term outcomes after colon cancer surgery.

Authors :: Shiraishi T
Tominaga T
Nonaka T
Hashimoto S
Hamada K
Araki M
Sumida Y
Takeshita H
Fukuoka H
Wada H
To K
Yamashita M
Tanaka K
Sawai T
Nagayasu T
Source :: PloS one [PLoS One] 2022 Jan 12; Vol. 17 (1), pp. e0262531. Date of Electronic Publication: 2022 Jan 12 (Print Publication: 2022).
Publication Year :: 2022
Abstract: Background: Hemodialysis patients who undergo surgery have a high risk of postoperative complications. The aim of this study was to determine whether colon cancer surgery can be safely performed in hemodialysis patients.<br />Methods: This multicenter retrospective study included 1372 patients who underwent elective curative resection surgery for colon cancer between April 2016 and March 2020.<br />Results: Of the total patients, 19 (1.4%) underwent hemodialysis, of whom 19 (100%) had poor performance status and 18 had comorbidities (94.7%). Minimally invasive surgery was performed in 78.9% of hemodialysis patients. The postoperative complication rate was significantly higher in hemodialysis than non-hemodialysis patients (36.8% vs. 15.5%, p = 0.009). All postoperative complications in the hemodialysis patients were infectious type. Multivariate analysis revealed a significant association of hemodialysis with complications (odds ratio, 2.9362; 95%CI, 1.1384-7.5730; p = 0.026).<br />Conclusion: Despite recent advances in perioperative management and minimally invasive surgery, it is necessary to be aware that short-term complications can still occur, especially infectious complications in hemodialysis patients.<br />Competing Interests: The authors have declared that no competing interests exist.