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What is the clinical impact of staging and surveillance PET-CT scan findings in patients with bone and soft tissue sarcoma?

Authors :
Lee L
Kazmer A
Colman MW
Gitelis S
Batus M
Blank AT
Source :
Journal of surgical oncology [J Surg Oncol] 2022 Apr; Vol. 125 (5), pp. 901-906. Date of Electronic Publication: 2022 Jan 13.
Publication Year :
2022

Abstract

Background and Objectives: Positron emission tomography-computerized tomography (PET-CTs) are becoming increasingly utilized in sarcoma care, workup, and surveillance. This study aimed to describe additional PET-CT findings as well as subsequent workups and changes in the clinical course due to those results.<br />Methods: Patient records were retrospectively reviewed, and the additional workups and evaluations triggered by PET-CT findings were qualitatively analyzed to document their results. Additional changes in the clinical course were documented.<br />Results: A total of 183 bone and soft tissue sarcoma patients underwent PET-CT as part of staging or surveillance. Additional workup was performed in 31.5% (n = 41 of 130) patients who had positive PET-CT findings. Among these, 36.6% (n = 15 of 41) patients had clinically significant findings that altered the clinical course. Overall, 14.8% (n = 27 of 183) experienced a change in the clinical course due to PET-CT.<br />Conclusion: PET-CT often highlights lesions of potential clinical importance. Additional workup, as well as changes in the clinical course, were not infrequent. Future, multi-institutional studies should address the value of PET-CT in sarcoma care.<br /> (© 2022 Wiley Periodicals LLC.)

Details

Language :
English
ISSN :
1096-9098
Volume :
125
Issue :
5
Database :
MEDLINE
Journal :
Journal of surgical oncology
Publication Type :
Academic Journal
Accession number :
35023167
Full Text :
https://doi.org/10.1002/jso.26789