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A prospective study of Salvia miltiorrhiza and Rhizoma chuanxiong preparation in the treatment of hypoparathyroidism after total thyroidectomy.
- Source :
-
Pakistan journal of pharmaceutical sciences [Pak J Pharm Sci] 2021 Nov; Vol. 34 (6(Special)), pp. 2385-2389. - Publication Year :
- 2021
-
Abstract
- This study aimed to investigate the clinical efficacy of Salvia miltiorrhiza and Rhizoma chuanxiong preparation on hypoparathyroidism. A total of 100 patients with hypoparathyroidism after total thyroidectomy were erolled, they were divided into the observation group (n=50), Salvia miltiorrhiza and Rhizoma chuanxiong preparation were added on the basis of traditional treatment. The control group (n=50), were treated with traditional treatment. To analyze the therapeutic effect of Salvia miltiorrhiza and Rhizoma chuanxiong preparation on hypoparathyroidism. After follow-up, the recovery time of parathyroid function in the observation group was significantly shorter than the control (P<0.05). No permanent hypoparathyroidism in the observation group and 4 cases in the control, which was statistically significant (P<0.05). The serum PTH in the observation group was significantly higher than the control on the 7th, 30th day, 3rd and 6th month. The level of serum calcium in the observation group was significantly higher than the control on the 3rd, 7th and 30th day (P<0.05). Salvia miltiorrhiza and Rhizoma chuanxiong preparation has obvious effects on the treatment of hypoparathyroidism and has low adverse reactions, which is worthy of clinical application.
- Subjects :
- Adult
Biomarkers blood
Calcium blood
Case-Control Studies
Drugs, Chinese Herbal adverse effects
Female
Humans
Hypoparathyroidism blood
Hypoparathyroidism diagnosis
Hypoparathyroidism etiology
Male
Middle Aged
Parathyroid Hormone blood
Time Factors
Treatment Outcome
Drugs, Chinese Herbal therapeutic use
Hypoparathyroidism drug therapy
Salvia miltiorrhiza
Thyroidectomy adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1011-601X
- Volume :
- 34
- Issue :
- 6(Special)
- Database :
- MEDLINE
- Journal :
- Pakistan journal of pharmaceutical sciences
- Publication Type :
- Academic Journal
- Accession number :
- 35039249