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Herbal compounds in the treatment of pulmonary silicosis.
- Source :
-
Physiological research [Physiol Res] 2021 Dec 31; Vol. 70 (S3), pp. S275-S287. - Publication Year :
- 2021
-
Abstract
- Herbal compounds including those already well-established in traditional Chinese medicine have been increasingly tested in the treatment of various diseases. Recent studies have shown that herbal compounds can be of benefit also for pulmonary silicosis as they can diminish changes associated with silica-induced inflammation, fibrosis, and oxidative stress. Due to a lack of effective therapeutic strategies, development of novel approaches which may be introduced particularly in the early stage of the disease, is urgently needed. This review summarizes positive effects of several alternative plant-based drugs in the models of experimental silicosis with a potential for subsequent clinical investigation and use in future.
- Subjects :
- Animals
Anti-Inflammatory Agents adverse effects
Humans
Inflammation Mediators metabolism
Lung metabolism
Lung pathology
Oxidative Stress drug effects
Plant Preparations adverse effects
Pulmonary Fibrosis metabolism
Pulmonary Fibrosis pathology
Reactive Oxygen Species metabolism
Silicosis metabolism
Silicosis pathology
Anti-Inflammatory Agents therapeutic use
Antioxidants therapeutic use
Lung drug effects
Plant Preparations therapeutic use
Pulmonary Fibrosis drug therapy
Silicosis drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1802-9973
- Volume :
- 70
- Issue :
- S3
- Database :
- MEDLINE
- Journal :
- Physiological research
- Publication Type :
- Academic Journal
- Accession number :
- 35099247
- Full Text :
- https://doi.org/10.33549/physiolres.934817