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Does Exercise Affect Telomere Length? A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
- Source :
-
Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2022 Feb 05; Vol. 58 (2). Date of Electronic Publication: 2022 Feb 05. - Publication Year :
- 2022
-
Abstract
- Background and objectives: Telomere length is an indicator of biological aging, and it shortens during cell division. A short telomere length is associated with various age-related diseases and mortality. It is suggested that physical activity has a positive effect on the rate of telomere length shortening. Materials and Methods: Related studies, published in electronic databases, were searched with keywords, including exercise, telomere length, and randomized controlled trial. The data were weighted and pooled through a fixed-effect model. Results: Of the total 49 studies searched, 7 studies with 939 participants were considered suitable, and were analyzed qualitatively and quantitatively. Exercise is beneficial to telomere length. Aerobic exercise was effective as the type of exercise (MD, -0.03; 95% CI, -0.04 to -0.01). In addition, exercise for more than 6 months, with a change in lifestyle, is beneficial for telomere length (MD, -0.02; 95% CI, -0.04 to -0.01). Conclusions: The type and duration of exercise for positive improvement in telomere length is aerobic exercise for more than 6 months.
- Subjects :
- Humans
Randomized Controlled Trials as Topic
Telomere genetics
Exercise
Life Style
Subjects
Details
- Language :
- English
- ISSN :
- 1648-9144
- Volume :
- 58
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Medicina (Kaunas, Lithuania)
- Publication Type :
- Academic Journal
- Accession number :
- 35208566
- Full Text :
- https://doi.org/10.3390/medicina58020242