Sleep Disturbances Linked to Genetic Disorders.

Authors :: Tedjasukmana R
Source :: Sleep medicine clinics [Sleep Med Clin] 2022 Mar; Vol. 17 (1), pp. 77-86. Date of Electronic Publication: 2022 Jan 03.
Publication Year :: 2022
Abstract: Genetic factors are surmised to regulate sleep as evidenced by the heritability of sleep traits, specific genetic polymorphisms of these traits, and familial sleep disorders. Sleep is also a very complex behavior that is regulated by circadian rhythm, homeostatic drive, and other processes. All these processes appear to have genetic factors; however, we still cannot elucidate sleep genes. Recent studies in humans and animal models have uncovered some genetic factors underlying sleep disturbances. In this review, we present an overview of genetical regulation of sleep and genetic factors underlying several sleep disturbances.<br />Competing Interests: Disclosure The author has nothing to disclose.<br /> (Copyright © 2021 Elsevier Inc. All rights reserved.)