89Zr-PSMA-617 PET/CT May Reveal Local Recurrence of Prostate Cancer Unidentified by 68Ga-PSMA-11 PET/CT.

Authors :: Rosar F
Bartholomä M
Maus S
Privé BM
Khreish F
Franssen GM
Derks YHW
Nagarajah J
Ezziddin S
Source :: Clinical nuclear medicine [Clin Nucl Med] 2022 May 01; Vol. 47 (5), pp. 435-436.
Publication Year :: 2022
Abstract: Abstract: For localization of biochemical recurrence of prostate cancer, 68Ga-PSMA-11 PET/CT imaging was performed in a 66-year-old man with no suspicious findings at 1 hour p.i. Additional 89Zr-PSMA-617 PET/CT revealed a small local recurrence in the prostate bed, facilitating consecutive local therapy. This interesting image points to the potential of PET/CT with 89Zr-labeled PSMA ligands, for example, 89Zr-PSMA-617, for identifying the source of biochemical recurrence despite otherwise negative imaging including conventional PSMA PET/CT.<br />Competing Interests: Conflicts of interest and sources of funding: none declared.<br /> (Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.)

Subjects :: Aged
Dipeptides
Edetic Acid
Gallium Isotopes
Gallium Radioisotopes
Heterocyclic Compounds, 1-Ring
Humans
Male
Neoplasm Recurrence, Local diagnostic imaging
Prostate-Specific Antigen
Radioisotopes
Zirconium
Positron Emission Tomography Computed Tomography methods
Prostatic Neoplasms diagnostic imaging

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