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Recurrence Patterns and Efficacy of Surveillance Modalities for Sinonasal Malignancies.
- Source :
-
American journal of rhinology & allergy [Am J Rhinol Allergy] 2022 Jul; Vol. 36 (4), pp. 473-479. Date of Electronic Publication: 2022 Mar 03. - Publication Year :
- 2022
-
Abstract
- Objective: There is limited information regarding the recurrence patterns and efficacy of surveillance modalities in patients with sinonasal malignancies.<br />Methods: A retrospective study was conducted between the years 2001-2018 at a tertiary care center. Included were all patients with sinonasal malignancies treated in our institution. Data regarding recurrence and survival were analyzed.<br />Results: Eighty-one patients were included. Multimodal treatment was administered to the majority of patients. 24 (35.3%) patients recurred with a median time of 17 months (range, 4-180). Although the majority of recurrences occurred within the first 5 years (83.3%), 4 (16.6%) recurred later on (5-15 years). Recurrences were local in 83.3%, regional in 20.8% and distant in 16.6%. All local recurrences occurred within the radiation treatment field and all patients with distant failure had mucosal melanoma. The majority of recurrences (70.6%) were diagnosed clinically or endoscopically, mainly in patients with SCC during the first 2 years of follow up. MRI or PET-CT were crucial in detecting extra-sinus and distant failures. Salvage surgery was feasible in the majority of patients (58.3%). Overall, 5 years survival (OS) rate was 60.9%.<br />Conclusions: Frequent clinic visits with nasal endoscopy combined with frequent imaging studies should be routinely practiced as part of a long-term surveillance plan. Longer follow up duration should be considered in these patients.<br />Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Subjects :
- Humans
Positron Emission Tomography Computed Tomography methods
Retrospective Studies
Magnetic Resonance Imaging methods
Neoplasm Recurrence, Local epidemiology
Paranasal Sinus Neoplasms diagnosis
Paranasal Sinus Neoplasms epidemiology
Paranasal Sinus Neoplasms therapy
Nose Neoplasms pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1945-8932
- Volume :
- 36
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- American journal of rhinology & allergy
- Publication Type :
- Academic Journal
- Accession number :
- 35238217
- Full Text :
- https://doi.org/10.1177/19458924221079963