Acute Myopic Shift and Internal Limiting Membrane Folds Linked to Topiramate Use: A Case Report.

Authors :: Dogan L
Source :: Beyoglu eye journal [Beyoglu Eye J] 2022 Feb 18; Vol. 7 (1), pp. 71-75. Date of Electronic Publication: 2022 Feb 18 (Print Publication: 2022).
Publication Year :: 2022
Abstract: We present a case report of a 26-year-old female patient with acute visual impairment, who had been treated with 50 mg/day topiramate for 5 days for migraine prophylaxis. Ocular examination showed bilateral anterior chamber narrowing and macular striae. She had no previous ocular pathology, but her cycloplegic refraction showed a myopic shift of about 6 D. Topiramate was stopped and the patient's unaided visual level and macular stria returned to normal with topical steroid and cyclopentolate treatment. Recognition of this side effect and discontinuation of the causative drug may prevent angle closure and related vision loss.<br />Competing Interests: Conflict of Interest: None declared.<br /> (Copyright: © 2022 by Beyoglu Eye Training and Research Hospital.)

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