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Hemopoietic stem cells "age" structure revealed by the exogenous colony forming method.

Authors :
Gaidul KV
Tsyrlova IG
Kozlov VA
Source :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 1986; Vol. 40 (3), pp. 114-5.
Publication Year :
1986

Abstract

The number of colony forming units in mice following the transplantation of cells of bone marrow, spleen and embryonal liver, forming exogenous spleen colonies on 5, 8 and 11 days has been determined. It has been shown that stem cell subpopulation forming colonies on 5 day (CFUs-5) was notable for lower capacity for self maintenance, and contained predominantly by erythroid colonies, these CFUs-5 were mainly in embryonal liver and less in reduced in the hemopoietic populations in mice.

Details

Language :
English
ISSN :
0753-3322
Volume :
40
Issue :
3
Database :
MEDLINE
Journal :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Publication Type :
Academic Journal
Accession number :
3527289