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[Pulmonary epithelioid hemangioendothelioma].

Authors :
Dvorakovskaya IV
Bugrov SN
Novikova LN
Skryabin SA
Ariel BM
Source :
Arkhiv patologii [Arkh Patol] 2022; Vol. 84 (2), pp. 29-35.
Publication Year :
2022

Abstract

The article describes the clinical, radiological and pathological features of epithelioid hemangioendothelioma (EHE) in 27 adult patients, mainly female. In all cases, with the exception of one, there was a benign course of the disease over many years with a tendency to stabilize growth, the morphological sign of which was the development of widespread sclerotic changes. With the help of immunohistochemical method, the endothelial nature of EHE cells and its relatively low proliferative potential were confirmed. Clinical and morphological features of EHE raise the question of the essence of proliferation of endothelial cells with the formation of tumor-like nodes. There is every reason to consider EHE as a pseudotumor of the type of nodose hyperplasia in the nosological group of dyshormonal hyperplasia, similar to benign leiomyoma of the uterus with lung damage, as we have previously proposed.

Details

Language :
Russian
ISSN :
0004-1955
Volume :
84
Issue :
2
Database :
MEDLINE
Journal :
Arkhiv patologii
Publication Type :
Academic Journal
Accession number :
35417946
Full Text :
https://doi.org/10.17116/patol20228402129