Back to Search
Start Over
Polypyrrole Cubosomes with Ordered Ultralarge Mesopore for Controllable Encapsulation and Release of Albumin.
Polypyrrole Cubosomes with Ordered Ultralarge Mesopore for Controllable Encapsulation and Release of Albumin.
- Source :
-
Nano letters [Nano Lett] 2022 May 11; Vol. 22 (9), pp. 3685-3690. Date of Electronic Publication: 2022 Apr 21. - Publication Year :
- 2022
-
Abstract
- Despite substantial progress in porous materials over past years, controllable preparation of conductive polymers (CPs) with continuous large pores is challenging, which are important for diverse applications, including energy storage, electrocatalysis, and biological separations. Here, we develop an unprecedented ordered bicontinuous mesoporous PPy cubosomes (mPPy-cs) using a soft-template strategy, resulting in ultralarge pores of ∼45 nm and high specific surface area of 69.5 m <superscript>2</superscript> g <superscript>-1</superscript> . Along with their unique characteristics of adjustable surface charges and sensitivity to pH, mPPy-cs exhibited a near quantitative adsorption of albumin within 30 min, enabling efficient separation from immunoglobulin G, a typical inclusion in commercial albumin products. Moreover, the absorbed albumin could be further released in a controlled manner by lowering the pH. This work provides a feasible strategy for bottom-up construction of CPs with tailored pore sizes and nanoarchitectures, expected to attract significant attention to their properties and applications.
- Subjects :
- Albumins
Surface Properties
Polymers chemistry
Pyrroles chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1530-6992
- Volume :
- 22
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Nano letters
- Publication Type :
- Academic Journal
- Accession number :
- 35446565
- Full Text :
- https://doi.org/10.1021/acs.nanolett.2c00330