OK-432 Treatment of Ranula Intruding into the Cervical Region.

Authors :: Ohta N
Shirane S
Fukase S
Kawata R
Sato T
Satani N
Suzuki T
Source :: Clinics and practice [Clin Pract] 2022 Mar 28; Vol. 12 (2), pp. 215-218. Date of Electronic Publication: 2022 Mar 28.
Publication Year :: 2022
Abstract: Objectives: Plunging ranula intruding into the cervical region is rare and a standard therapy has not yet been consolidated. This paper investigates the outcomes and side effects of OK-432 treatment in patients with a ranula extending into the cervical region.<br />Methods: The study design and setting consisted of a planned data collection at Tohoku Medical and Pharmaceutical University and Fukase Clinic. Eight patients with ranula extending into the cervical region received OK-432 treatment between January 2016 and February 2019. OK-432 treatment was performed for patients with ranula extending into the cervical region.<br />Results: In all patients, a total shrinkage and marked reduction in lesions were observed without local scars or deformations after OK-432 treatment. Complications were local swelling and mild fever (37.5-38.5 °C), which lasted a few days in half of the patients.<br />Conclusions: OK-432 treatment is straightforward, secure, and efficacious and can be substituted for surgery in the treatment of ranula extending into the cervical region.