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Preemptive analgesia with ibuprofen increases anesthetic efficacy in children with severe molar: a triple-blind randomized clinical trial.

Authors :
Vicioni-Marques F
Paula-Silva FWG
Carvalho MR
Queiroz AM
Freitas O
Duarte MPF
Manton DJ
Carvalho FK
Source :
Journal of applied oral science : revista FOB [J Appl Oral Sci] 2022 Apr 20; Vol. 30, pp. e20210538. Date of Electronic Publication: 2022 Apr 20 (Print Publication: 2022).
Publication Year :
2022

Abstract

Molar incisor hypomineralization (MIH) is often accompanied by dental hypersensitivity and difficulty in achieving effective analgesia.<br />Objective: This study evaluated the effectiveness of preemptive analgesia in children with severe MIH, post-eruptive enamel breakdown, and hypersensitivity.<br />Methodology: Ibuprofen (10 mg/kg child weight) or placebo was administered, followed by infiltrative anesthesia and restoration with resin composite. Hypersensitivity was evaluated in five moments. The data were analyzed using the chi-square test, Fisher's exact test, and t-test.<br />Results: Preemptive analgesia provided benefits for the treatment of severe cases of MIH, with an increase in the effectiveness of infiltrative anesthesia and improved patient comfort during the restorative procedure.<br />Conclusion: Preemptive analgesia has shown efficacy in reducing hypersensitivity during restorative dental procedures, evidencing the significance of this study for patients with MIH and hypersensitivity.

Details

Language :
English
ISSN :
1678-7765
Volume :
30
Database :
MEDLINE
Journal :
Journal of applied oral science : revista FOB
Publication Type :
Academic Journal
Accession number :
35476115
Full Text :
https://doi.org/10.1590/1678-7757-2021-0538