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Longitudinal analysis of built environment and aerosol contamination associated with isolated COVID-19 positive individuals.
- Source :
-
Scientific reports [Sci Rep] 2022 May 05; Vol. 12 (1), pp. 7395. Date of Electronic Publication: 2022 May 05. - Publication Year :
- 2022
-
Abstract
- The indoor environment is the primary location for the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), largely driven by respiratory particle accumulation in the air and increased connectivity between the individuals occupying indoor spaces. In this study, we aimed to track a cohort of subjects as they occupied a COVID-19 isolation dormitory to better understand the impact of subject and environmental viral load over time, symptoms, and room ventilation on the detectable viral load within a single room. We find that subject samples demonstrate a decrease in overall viral load over time, symptoms significantly impact environmental viral load, and we provide the first real-world evidence for decreased aerosol SARS-CoV-2 load with increasing ventilation, both from mechanical and window sources. These results may guide environmental viral surveillance strategies and be used to better control the spread of SARS-CoV-2 within built environments and better protect those caring for individuals with COVID-19.<br /> (© 2022. The Author(s).)
- Subjects :
- Aerosols
Built Environment
Humans
SARS-CoV-2
Ventilation
COVID-19
Subjects
Details
- Language :
- English
- ISSN :
- 2045-2322
- Volume :
- 12
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Scientific reports
- Publication Type :
- Academic Journal
- Accession number :
- 35513399
- Full Text :
- https://doi.org/10.1038/s41598-022-11303-8