Developments in high-throughput functional epigenomics: CRISPR-single-cell assay for transposase-accessible chromatin using sequencing screens.

Authors :: E Yan R
P Greenfield J
Dahmane N
Source :: Epigenomics [Epigenomics] 2022 Jun; Vol. 14 (11), pp. 645-649. Date of Electronic Publication: 2022 May 16.
Publication Year :: 2022
Abstract: Tweetable abstract CRISPR-scATAC-seq screens pave the way for high-throughput functional epigenomics by linking perturbations to a broad view of epigenetic state and messages hidden within accessible sequences.

Subjects :: Chromatin Immunoprecipitation Sequencing
Clustered Regularly Interspaced Short Palindromic Repeats
High-Throughput Nucleotide Sequencing
Humans
Sequence Analysis, DNA
Transposases genetics
Transposases metabolism
Chromatin genetics
Epigenomics

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