Subungual Pigmented Squamous Cell Carcinoma in a Dog.

Authors :: Yang Y
Go DM
Jung JH
Seo D
Hwang SH
Lee M
Kim DY
Kim Y
Source :: Journal of comparative pathology [J Comp Pathol] 2022 Jun; Vol. 194, pp. 50-53. Date of Electronic Publication: 2022 Apr 27.
Publication Year :: 2022
Abstract: An 11-year-old spayed female Miniature Schnauzer dog was presented with loss of a claw caused by a nail bed mass. Histopathological evaluation revealed that the mass comprised neoplastic squamous cells with abundant cytoplasmic melanin pigment. Immunohistochemically, the neoplastic cells were positive for cytokeratin and negative for vimentin and ionized calcium-binding adaptor molecule 1, supporting a diagnosis of pigmented squamous cell carcinoma. To our knowledge, this is the first report of subungual pigmented squamous cell carcinoma in animals.<br /> (Copyright © 2022 Elsevier Ltd. All rights reserved.)