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Association of PTSD With Longitudinal COVID-19 Burden in a Mixed-Serostatus Cohort of Men and Women: Weathering the Storm.
- Source :
-
Journal of acquired immune deficiency syndromes (1999) [J Acquir Immune Defic Syndr] 2022 Aug 15; Vol. 90 (5), pp. 567-575. - Publication Year :
- 2022
-
Abstract
- Objectives: This study of people with HIV (PWH) and those without HIV conducted during the COVID-19 pandemic in the United States in 2020 examines the impact of posttraumatic stress disorder (PTSD) on COVID-19 burden, defined as pandemic-related disruptions.<br />Methods: Data consisted of survey responses on PTSD among participants (N = 2434) enrolled in the Multicenter AIDS Cohort Study (MACS) and the Women's Interagency HIV (WIHS) cohorts. Unadjusted and adjusted regression models were used to examine the association of PTSD with COVID-19 burden (overall and domain-specific burdens). Quasi-Poisson regression models were used to assess associations with the COVID-19 burden score and 2 domain-specific burdens: (1) changes in resources and (2) interruptions in health care. Analyses was adjusted for age, race/ethnicity, HIV serostatus, current smoking status, number of comorbidities, education, and study regions.<br />Results: Study participants were a median age of 58 (interquartile range, 52-65) years. In both bivariate and multivariable models, PTSD severity was associated with greater overall COVID-19 burden. PTSD severity was associated with the number of resource changes and number of interruptions in medical care. These findings were also consistent across cohorts (MACS/WIHS) and across HIV serostatus, suggesting a greater risk for COVID-19 burden with greater PTSD severity, which remained significant after controlling for covariates.<br />Conclusions: This study builds on emerging literature demonstrating the impact of mental health on the burden and disruption associated with the COVID-19 pandemic, providing context specific to PWH. The ongoing pandemic requires structural and social interventions to decrease disruption to resources and health resource needs among these vulnerable populations.<br />Competing Interests: The authors have no conflicts of interest to disclose.<br /> (Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.)
- Subjects :
- Aged
Cohort Studies
Female
Humans
Male
Middle Aged
Pandemics
United States epidemiology
COVID-19 epidemiology
HIV Infections complications
HIV Infections epidemiology
HIV Infections psychology
Stress Disorders, Post-Traumatic complications
Stress Disorders, Post-Traumatic epidemiology
Stress Disorders, Post-Traumatic psychology
Subjects
Details
- Language :
- English
- ISSN :
- 1944-7884
- Volume :
- 90
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Journal of acquired immune deficiency syndromes (1999)
- Publication Type :
- Academic Journal
- Accession number :
- 35585664
- Full Text :
- https://doi.org/10.1097/QAI.0000000000003006