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Hepatitis B, C, and D Virus Infections and AFP Tumor Marker Prevalence Among the Elderly Population in Mongolia: A Nationwide Survey.
- Source :
-
Journal of preventive medicine and public health = Yebang Uihakhoe chi [J Prev Med Public Health] 2022 May; Vol. 55 (3), pp. 263-272. Date of Electronic Publication: 2022 May 20. - Publication Year :
- 2022
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Abstract
- Objectives: Infections with hepatitis B, C, and D virus (HBV, HCV, and HDV) are a major public health problem and lead to serious complications such as cirrhosis and hepatocellular carcinoma. We aimed to determine the seroprevalence of hepatitis B surface antigen (HBsAg), anti-HCV, anti-HDV immunoglobulin G, alpha-fetoprotein (AFP), and dual and triple hepatitis virus infections in Mongolia.<br />Methods: A total of 2313 participants from urban and rural regions were randomly recruited for this cross-sectional study. A questionnaire was used to identify the risk factors for hepatitis virus infections, and the seromarkers were measured using immunoassay kits.<br />Results: Among all participants, the prevalence of HBV, HCV, and HDV was 15.6%, 36.6%, and 14.3%, respectively. The infection rates were significantly higher in females and participants with a lower education level, rural residence, older age, and a history of blood transfusion. HBV and HCV co-infection was found in 120 (5.2%) participants and HBV, HCV, and HDV triple infection was detected in 67 (2.9%) participants. The prevalence of elevated AFP was 2.7%, 5.5%, and 2.6% higher in participants who were seropositive for HBsAg (p=0.01), anti-HCV (p<0.001), and anti-HDV (p=0.022), respectively. Elevated AFP was more prevalent in participants co-infected with HBV and HCV (5.8%, p=0.023), HBV and HDV (6.0%, p<0.001), and triple-infected with HBV, HCV, and HDV (7.5%) than in uninfected individuals.<br />Conclusions: Nearly half (49.8%) of the study population aged ≥40 years were infected with HBV, HCV, or HDV, and 22.4% had dual or triple infections.
- Subjects :
- Aged
Biomarkers, Tumor
Cross-Sectional Studies
Female
Hepatitis Antibodies
Hepatitis B Surface Antigens
Hepatitis B virus
Hepatitis C Antibodies
Hepatitis Delta Virus
Humans
Mongolia epidemiology
Prevalence
Seroepidemiologic Studies
Surveys and Questionnaires
alpha-Fetoproteins
Hepatitis B complications
Hepatitis B epidemiology
Hepatitis C complications
Hepatitis C epidemiology
Virus Diseases complications
Subjects
Details
- Language :
- English
- ISSN :
- 2233-4521
- Volume :
- 55
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of preventive medicine and public health = Yebang Uihakhoe chi
- Publication Type :
- Academic Journal
- Accession number :
- 35678000
- Full Text :
- https://doi.org/10.3961/jpmph.21.573