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Monoclonal antibodies for mild-to-moderate COVID-19 in multiple sclerosis: A case series.

Authors :
Moccia M
Buonomo AR
Scotto R
Viceconte G
Nobile M
Lanzillo R
Brescia Morra V
Gentile I
Source :
Journal of the neurological sciences [J Neurol Sci] 2022 Aug 15; Vol. 439, pp. 120306. Date of Electronic Publication: 2022 Jun 02.
Publication Year :
2022

Abstract

We reported on five people with MS, using immunodepleting disease modifying treatments (anti-CD20 monoclonal antibodies and sphingosine-one-phosphate modulators) and with reduced COVID-19 vaccine response, who had mild-to-moderate symptomatic COVID-19, and were treated with anti-SARS-CoV-2 monoclonal antibodies. In particular, we showed the possibility to use monoclonal antibodies to speed-up recovery from COVID-19 in MS, in the absence of any COVID-19 residuals or MS changes (e.g., relapses or disability).<br /> (Copyright © 2022 Elsevier B.V. All rights reserved.)

Details

Language :
English
ISSN :
1878-5883
Volume :
439
Database :
MEDLINE
Journal :
Journal of the neurological sciences
Publication Type :
Academic Journal
Accession number :
35689866
Full Text :
https://doi.org/10.1016/j.jns.2022.120306