Two new aspidosperma-type monoterpenoid indole alkaloids from Ervatamia officinalis .

Authors :: Li BJ
Ma Y
Qian HS
He HP
Huang CH
Yu GD
Tang BQ
Source :: Journal of Asian natural products research [J Asian Nat Prod Res] 2022 Jun 23, pp. 1-7. Date of Electronic Publication: 2022 Jun 23.
Publication Year :: 2022
Publisher :: Ahead of Print
Abstract: Two new aspidosperma-type monoterpenoid indole alkaloids, 16- O -methylvoafinine ( 1 ) and 14,15- diepi -voafinidine ( 2 ) were isolated from the aerial parts of Ervatamia officinalis . Their structures were established by comprehensive spectroscopic analysis including 1D and 2D NMR, HR-ESI-MS, and electronic circular dichroism calculation. The isolated compounds were evaluated for cytotoxic activities against HepG2, MCF-7, and A549 cell lines by CCK-8 assay.

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