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Biomarkers for Early Diagnosis of Ovarian Carcinoma.

Authors :
Manasa G
Mascarenhas RJ
Shetti NP
Malode SJ
Aminabhavi TM
Source :
ACS biomaterials science & engineering [ACS Biomater Sci Eng] 2022 Jul 11; Vol. 8 (7), pp. 2726-2746. Date of Electronic Publication: 2022 Jun 28.
Publication Year :
2022

Abstract

The leading cause of gynecological cancer-related morbidity and mortality is ovarian cancer (OC), which is dubbed a silent killer. Currently, OC is a target of intense biomarker research, because it is often not discovered until the disease is advanced. The goal of OC research is to develop effective tests using biomarkers that can detect the disease at the earliest stages, which would eventually decrease the mortality, thereby preventing recurrence. Therefore, there is a pressing need to revisit the existing biomarkers to recognize the potential biomarkers that can lead to efficient predictors for the OC diagnosis. This Perspective covers an update on the currently available biomarkers used in the triaging of OC to gain certain insights into the potential role of these biomarkers and their estimation that are crucial to the understanding of neoplasm progression, diagnostics, and therapy.

Details

Language :
English
ISSN :
2373-9878
Volume :
8
Issue :
7
Database :
MEDLINE
Journal :
ACS biomaterials science & engineering
Publication Type :
Academic Journal
Accession number :
35762531
Full Text :
https://doi.org/10.1021/acsbiomaterials.2c00390