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[Lung cancer at a Chilean public hospital].

Authors :: González L R
Barra M S
Riquelme U A
Reyes M R
Spencer L ML
Alarcón O F
Seguel S E
Stockins L A
Jadue T A
Saldivia Z D
Schaub C A
Alarcón C E
Source :: Revista medica de Chile [Rev Med Chil] 2022 Jan; Vol. 150 (1), pp. 7-16.
Publication Year :: 2022
Abstract: Background: Lung cancer is the world's leading cause of cancer death.<br />Aim: To describe the clinical, staging and survival characteristics of lung cancer in a public Chilean regional hospital.<br />Material and Methods: Analysis of a prospective database of a thoracic surgery service, retrieving histologically confirmed lung cancer cases from January 2010 to December 2019 and reviewing their medical records. Cases were re-staged by the TNM-8 system and variables were compared between periods 2010-2014 and 2015-2019.<br />Results: We retrieved 551 lung cancer cases, 333 (60 %) men, with a mean age of 65 years. Distant metastases were found in 72% of cases (excluding lymphatic metastases). Of the non-small cell lung cancers (NSCLC), 50 (10%) cases were in stage I, 18 (4%) in stage II, 81 (16%) in stage III and 347 (70%) in stage IV. Global five-year survival was 18%, 20% for NSCLC, 71% for excised NSCLC, 8% for non-excised NSCLC, 88% for stage I and 92% for subgroup IA. Resective surgery was performed in 81 (14%) cases. When comparing 2010-2014 and 2015-2019 periods, the frequency of resective surgery increased from 7% to 20%.<br />Conclusions: The diagnosis of lung cancer was frequently made in advanced stages. There was a significant increase in early diagnosis and frequency of surgeries with curative intent in the second observation period.