Saturation of ara-CTP accumulation during high-dose ara-C therapy: pharmacologic rationale for intermediate-dose ara-C.

Authors :: Plunkett W
Liliemark JO
Estey E
Keating MJ
Source :: Seminars in oncology [Semin Oncol] 1987 Jun; Vol. 14 (2 Suppl 1), pp. 159-66.
Publication Year :: 1987

Subjects :: Cytarabine metabolism
Dose-Response Relationship, Drug
Drug Administration Schedule
Humans
Infusions, Intravenous
Leukemia metabolism
Metabolic Clearance Rate
Arabinofuranosylcytosine Triphosphate metabolism
Arabinonucleotides metabolism
Cytarabine administration & dosage
Leukemia drug therapy

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