Back to Search Start Over

Initial introduction and spread of the SARS-CoV-2 AY.4.2.1 Delta variant in Bulgaria, a genomic insight.

Authors :
Alexiev I
Giovanetti M
Cella E
Ivanov I
Stoikov I
Donchev D
Grigorova L
Gancheva A
Dimitrova R
Korsun N
Trifonova I
Philipova I
Dobrinov V
Grigorova I
Kantardjiev T
Christova I
Ciccozzi M
Source :
Journal of medical virology [J Med Virol] 2022 Dec; Vol. 94 (12), pp. 6060-6064. Date of Electronic Publication: 2022 Aug 10.
Publication Year :
2022

Abstract

The evolution of the emerging SARS-CoV-2 variants carrying mutations in the spike protein raises concerns about the possibility of accelerated transmission in the ever-evolving COVID-19 pandemic worldwide. AY.4.2, a sublineage of the Delta variant, was considered a variant under investigation (VUI) and also gained the nickname "Delta Plus," due to its extra mutations, Y145H and A222V. In this study, using genomic epidemiology, we provide the first insights into the introduction of AY.4.2 in Bulgaria and the AY.4.2.1 sublineage that found larger dissemination only in Bulgaria and the United Kingdom.<br /> (© 2022 Wiley Periodicals LLC.)

Details

Language :
English
ISSN :
1096-9071
Volume :
94
Issue :
12
Database :
MEDLINE
Journal :
Journal of medical virology
Publication Type :
Academic Journal
Accession number :
35902787
Full Text :
https://doi.org/10.1002/jmv.28033