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The Leipzig Health Atlas-An Open Platform to Present, Archive, and Share Biomedical Data, Analyses, and Models Online.

Authors :
Kirsten T
Meineke FA
Loeffler-Wirth H
Beger C
Uciteli A
Stäubert S
Löbe M
Hänsel R
Rauscher FG
Schuster J
Peschel T
Herre H
Wagner J
Zachariae S
Engel C
Scholz M
Rahm E
Binder H
Loeffler M
Source :
Methods of information in medicine [Methods Inf Med] 2022 Dec; Vol. 61 (S 02), pp. e103-e115. Date of Electronic Publication: 2022 Aug 01.
Publication Year :
2022

Abstract

Background: Clinical trials, epidemiological studies, clinical registries, and other prospective research projects, together with patient care services, are main sources of data in the medical research domain. They serve often as a basis for secondary research in evidence-based medicine, prediction models for disease, and its progression. This data are often neither sufficiently described nor accessible. Related models are often not accessible as a functional program tool for interested users from the health care and biomedical domains.<br />Objective: The interdisciplinary project Leipzig Health Atlas (LHA) was developed to close this gap. LHA is an online platform that serves as a sustainable archive providing medical data, metadata, models, and novel phenotypes from clinical trials, epidemiological studies, and other medical research projects.<br />Methods: Data, models, and phenotypes are described by semantically rich metadata. The platform prefers to share data and models presented in original publications but is also open for nonpublished data. LHA provides and associates unique permanent identifiers for each dataset and model. Hence, the platform can be used to share prepared, quality-assured datasets and models while they are referenced in publications. All managed data, models, and phenotypes in LHA follow the FAIR principles, with public availability or restricted access for specific user groups.<br />Results: The LHA platform is in productive mode (https://www.health-atlas.de/). It is already used by a variety of clinical trial and research groups and is becoming increasingly popular also in the biomedical community. LHA is an integral part of the forthcoming initiative building a national research data infrastructure for health in Germany.<br />Competing Interests: None declared.<br /> (The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).)

Subjects

Subjects :
Germany
Prospective Studies

Details

Language :
English
ISSN :
2511-705X
Volume :
61
Issue :
S 02
Database :
MEDLINE
Journal :
Methods of information in medicine
Publication Type :
Academic Journal
Accession number :
35915977
Full Text :
https://doi.org/10.1055/a-1914-1985