Back to Search Start Over

Synthesis and characterization of a fluorescent steroid dimer linked through C-19 by a 1,4-Bis(phenylethynyl)phenylene fragment.

Authors :
Vazquez-Chavez J
Aguilar-Granda A
Iglesias Arteaga MA
Source :
Steroids [Steroids] 2022 Nov; Vol. 187, pp. 109098. Date of Electronic Publication: 2022 Aug 12.
Publication Year :
2022

Abstract

The synthesis and characterization of a dimer in which two nuclei of 3β-acetoxy-19-hydroxyandrost-5-en-17-one are linked by the fluorescent 1,4-bis(phenylethynyl)phenylene bridge attached to the oxygenated functions at positions C-19 of each steroid fragment is described. The compound was obtained in five steps and 23 % overall yield and showed a strong blue emission with a quantum yield of 0.66.<br />Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br /> (Copyright © 2022 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1878-5867
Volume :
187
Database :
MEDLINE
Journal :
Steroids
Publication Type :
Academic Journal
Accession number :
35964795
Full Text :
https://doi.org/10.1016/j.steroids.2022.109098