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Synthesis and characterization of a fluorescent steroid dimer linked through C-19 by a 1,4-Bis(phenylethynyl)phenylene fragment.
- Source :
-
Steroids [Steroids] 2022 Nov; Vol. 187, pp. 109098. Date of Electronic Publication: 2022 Aug 12. - Publication Year :
- 2022
-
Abstract
- The synthesis and characterization of a dimer in which two nuclei of 3β-acetoxy-19-hydroxyandrost-5-en-17-one are linked by the fluorescent 1,4-bis(phenylethynyl)phenylene bridge attached to the oxygenated functions at positions C-19 of each steroid fragment is described. The compound was obtained in five steps and 23 % overall yield and showed a strong blue emission with a quantum yield of 0.66.<br />Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br /> (Copyright © 2022 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1878-5867
- Volume :
- 187
- Database :
- MEDLINE
- Journal :
- Steroids
- Publication Type :
- Academic Journal
- Accession number :
- 35964795
- Full Text :
- https://doi.org/10.1016/j.steroids.2022.109098