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Mitochondrial Dysregulation and the Influence in Neurodegenerative Diseases.

Authors :
Zuccoli GS
Carregari VC
Source :
Advances in experimental medicine and biology [Adv Exp Med Biol] 2022; Vol. 1382, pp. 109-118.
Publication Year :
2022

Abstract

Mitochondrial function is essential to ensure vital cellular processes. Given the energy requirement of the brain, neuronal function, viability, and survival are closely related to proper mitochondrial function. Dysregulation of mitochondrial processes can lead to several detrimental effects in the cells and stablish the condition of mitochondrial dysfunction. This dysfunction is proposed to be greatly implicated in several neurodegenerative diseases, with evidence of compromised mitochondrial function and dynamics in Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis.<br /> (© 2022. The Author(s), under exclusive license to Springer Nature Switzerland AG.)

Details

Language :
English
ISSN :
0065-2598
Volume :
1382
Database :
MEDLINE
Journal :
Advances in experimental medicine and biology
Publication Type :
Academic Journal
Accession number :
36029407
Full Text :
https://doi.org/10.1007/978-3-031-05460-0_8