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[Broadening NIPT needs more care].

Authors :
Dondorp WJ
de Wert GMWR
Ploem CMC
Source :
Nederlands tijdschrift voor geneeskunde [Ned Tijdschr Geneeskd] 2022 Jul 12; Vol. 166. Date of Electronic Publication: 2022 Jul 12.
Publication Year :
2022

Abstract

In a research setting (TRIDENT-2), Dutch pregnant women undergoing prenatal screening for trisomies 21, 18 and 13 with the Non-Invasive Prenatal Test (NIPT), are offered the choice to also receive information about incidental findings. In a recent report, the Health Council of the Netherlands has recommended to retain this option, but to only report those incidental findings that very probably will lead to serious health outcomes for the child. A working group has been appointed to draw up a guideline for this. In this article we argue that actively searching for desired 'incidental findings' in fact amounts to broadening the scope of the screening and that a justification of this choice is still lacking. A core issue is whether the benefits of such broader screening outweigh the drawback of inevitably also generating findings that do not fit in with the aim of the screening: providing meaningful reproductive choices.

Details

Language :
Dutch; Flemish
ISSN :
1876-8784
Volume :
166
Database :
MEDLINE
Journal :
Nederlands tijdschrift voor geneeskunde
Publication Type :
Academic Journal
Accession number :
36036688