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Lead Optimization of Nerve-Specific Fluorophores for Image-Guided Nerve Sparing Surgical Procedures.

Authors :
Barth CW
Wang LG
Montano A
Antaris AL
Klaassen A
Sorger J
Kerr DA
Henderson ER
Alani AWG
Gibbs SL
Source :
Optical molecular probes, imaging and drug delivery [Opt Mol Probes Imaging Drug Deliv] 2021 Apr; Vol. 2021.
Publication Year :
2021

Abstract

Nerve damage is a major complication of surgery, causing pain and loss of function. We have identified novel near-infrared nerve-specific fluorophores that provide excellent nerve contrast with the ability to identify buried nerve tissue.

Details

Language :
English
Volume :
2021
Database :
MEDLINE
Journal :
Optical molecular probes, imaging and drug delivery
Publication Type :
Academic Journal
Accession number :
36053248
Full Text :
https://doi.org/10.1364/OMP.2021.OW3E.3