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Simultaneous affinity maturation and developability enhancement using natural liability-free CDRs.
- Source :
-
MAbs [MAbs] 2022 Jan-Dec; Vol. 14 (1), pp. 2115200. - Publication Year :
- 2022
-
Abstract
- Abbreviations: CDR: complementarity determining region; FACS: fluorescence-activated cell sorting; k <subscript>a</subscript> : association rate; k <subscript>d</subscript> : dissociation rate; K <subscript>D</subscript> : dissociation constant; scFv: single-chain variable fragment; SPR: surface plasmon resonance.
Details
- Language :
- English
- ISSN :
- 1942-0870
- Volume :
- 14
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- MAbs
- Publication Type :
- Academic Journal
- Accession number :
- 36068722
- Full Text :
- https://doi.org/10.1080/19420862.2022.2115200