18 F-FDG and 68 Ga-FAPI-04 PET/CT Imaging of a Case With Immunoglobulin G4-Related Disease Presenting as Hepatic Masses.

Abstract: Two hepatic masses were discovered through ultrasonography in a 50-year-old man with increased CA19-9, which is highly suspicious for malignancy. PET/CT images revealed intense 18 F-FDG and 68 Ga-FAPI-04 uptake in intrahepatic lesions. Histopathology with biopsy confirmed the diagnosis of immunoglobulin G4 (IgG4)-related disease. Here, we reported a case of IgG4-related primary localized pseudotumor without any other organ involvement. We concluded that in clinical work, if intrahepatic masses show high uptake of 18 F-FDG or 68 Ga-FAPI-04, intrahepatic IgG4-related disease should be considered for differential diagnosis.
Competing Interests: Conflicts of interest and sources of funding: The authors declare that they have no conflicts of interest. This work is supported by the “234 Discipline Climbing Plan” of the First Affiliated Hospital of Naval Medical University (grant no. 2019YPT002 and 2020YPT002). None declared to all authors.
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