Antiretroviral therapy achieved metabolic complete remission of hepatic AIDS related Epstein-Barr virus-associated smooth muscle tumor.

Authors :: Ara T
Endo T
Goto H
Kasahara K
Hasegawa Y
Yokoyama S
Shiratori S
Nakagawa M
Kuwahara K
Takakuwa E
Hashino S
Teshima T
Source :: Antiviral therapy [Antivir Ther] 2022 Oct; Vol. 27 (5), pp. 13596535221126828.
Publication Year :: 2022
Abstract: Epstein-Barr virus-associated smooth muscle tumor (EBV-SMT) is a rare mesenchymal tumor which occurs in immunocompromised patients. The immune status is an important factor in the treatment of EBV-SMTs, but the efficacy of antiretroviral therapy (ART) is not elucidated in acquired immune deficiency syndrome (AIDS) related EBV-SMTs. Here, we report the first successful case of a 29-year-old man with hepatic AIDS related EBV-SMT treated with ART solely. Positron emission tomography scan was useful for the evaluation of disease status. Recent advances in ART that enables to restore patient's immune status rapidly may change the treatment strategy in AIDS related EBV-SMT.

Subjects :: Adult
Herpesvirus 4, Human
Humans
Male
Acquired Immunodeficiency Syndrome complications
Acquired Immunodeficiency Syndrome drug therapy
Epstein-Barr Virus Infections complications
Epstein-Barr Virus Infections drug therapy
HIV Infections complications
HIV Infections drug therapy
Smooth Muscle Tumor drug therapy
Smooth Muscle Tumor pathology

Full Text Access

Tools