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Ten new prenylated flavonoids from Macaranga denticulata and their antitumor activities.
- Source :
-
Fitoterapia [Fitoterapia] 2022 Oct; Vol. 162, pp. 105302. Date of Electronic Publication: 2022 Sep 16. - Publication Year :
- 2022
-
Abstract
- Ten new prenylated flavonoids, named denticulains A-J (1-10), together with seven known prenylated flavonoids (11-17) were isolated from Macaranga denticulata. Their structures were elucidated on the basis of detailed spectroscopic analysis and by comparison with literature data. In addition, compounds 1 and 14 inhibited the proliferation of SW620 and HCT-116 cell lines with an IC <subscript>50</subscript> value of 46.08 μM and 56.83 μM, respectively.<br />Competing Interests: Declaration of Competing Interest The authors have declared that there is no conflict of interest.<br /> (Copyright © 2022. Published by Elsevier B.V.)
Details
- Language :
- English
- ISSN :
- 1873-6971
- Volume :
- 162
- Database :
- MEDLINE
- Journal :
- Fitoterapia
- Publication Type :
- Academic Journal
- Accession number :
- 36116613
- Full Text :
- https://doi.org/10.1016/j.fitote.2022.105302