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A rare case of metastatic paraspinal rhabdomyosarcoma presenting with proptosis in an adult patient.

Authors :
Chanda UL
Knapp C
Source :
Orbit (Amsterdam, Netherlands) [Orbit] 2024 Apr; Vol. 43 (2), pp. 280-282. Date of Electronic Publication: 2022 Sep 21.
Publication Year :
2024

Abstract

Secondary metastasis of rhabdomyosarcoma (RMS) to the orbit from a distant primary site is extremely rare in adults. In this article, we describe the case of a 24-year-old male presenting with proptosis, diplopia, and headaches concurrently with a histologically confirmed diagnosis of PAX3-FOXO1 positive paraspinal alveolar rhabdomyosarcoma. An orbital MRI revealed a fusiform mass arising from the inferior rectrus, displaying necrotic and irregular morphology consistent with malignancy. The patient is currently undergoing intensive chemotherapy. The objective of this case report is to highlight the rarity of an extraocular metastasis of RMS in an adult patient, alongside the importance of considering metastatic disease in a patient with fulminant unilateral proptosis.

Details

Language :
English
ISSN :
1744-5108
Volume :
43
Issue :
2
Database :
MEDLINE
Journal :
Orbit (Amsterdam, Netherlands)
Publication Type :
Academic Journal
Accession number :
36131600
Full Text :
https://doi.org/10.1080/01676830.2022.2125537