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Small Molecules Pushing Erythroid/Megakaryocyte Cell Specification Boundaries.

Authors :
Flygare J
Source :
Cellular reprogramming [Cell Reprogram] 2022 Oct; Vol. 24 (5), pp. 225-227.
Publication Year :
2022

Abstract

A combination of a MEK/ERK-signaling inhibitor and three chromatin-remodeling molecules enhances generation of platelet-producing megakaryocytes in vitro , possibly through direct reprogramming.

Details

Language :
English
ISSN :
2152-4998
Volume :
24
Issue :
5
Database :
MEDLINE
Journal :
Cellular reprogramming
Publication Type :
Periodical
Accession number :
36219716
Full Text :
https://doi.org/10.1089/cell.2022.0107