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Colony-forming activity of pluripotent stem cells in tolerant mice following antigen exposure.

Authors :
Kozlov VA
Tsyrlova IG
Gaidul KV
Source :
Folia biologica [Folia Biol (Praha)] 1987; Vol. 33 (3), pp. 207-10.
Publication Year :
1987

Abstract

The effect of sheep red blood cells (SRBC) and human red blood cells (HRBC) on the number of CFU-S in the bone marrow and spleen of (CBA X C57BL/6)F1 mice tolerant to SRBC was examined. The number of bone marrow and spleen CFU-S in SRBC tolerant mice was increased after injection of HRBC. After challenge with SRBC, CFU-S number was elevated in the spleen but not in the bone marrow. Thus, the mechanism of CFU-S activation in response to antigen exposure is different in the bone marrow and spleen.

Details

Language :
English
ISSN :
0015-5500
Volume :
33
Issue :
3
Database :
MEDLINE
Journal :
Folia biologica
Publication Type :
Academic Journal
Accession number :
3622853