Associations between short-term exposure to ambient PM 2.5 and incident cases of cerebrovascular disease in Yantai, China.

There are limited studies examining the association between PM _2.5 exposure and incident cerebrovascular disease (CD) cases in China. In this study, daily counts of incident CD cases and daily PM _2.5 concentrations were obtained in Yantai, Shandong Province, China from 2014 to 2019. We used a combination of the Poisson-distribution generalized linear model (GLM) and a distributed lag nonlinear model (DLNM) to examine the association of short-term exposure to ambient PM _2.5 and incident cases of CD. The results revealed that for every 10 μg/m ³ increment of PM _2.5 would increase the incident CD cases by 0.216% (RR:1.00216, 95%CI:1.0016-1.0028) at lag4. The stratified analysis demonstrated that the females and residents aged 65 years or above presented higher short-term PM _2.5 -associated CD risks than the males and aged below 65 years. Targeted prevention strategies should be adopted to reduce the PM _2.5 -related CD burden, especially for the susceptible population in China.
(© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)