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Role of Nutrients and Foods in Attenuation of Cardiac Remodeling through Oxidative Stress Pathways.

Authors :
Lazzarin T
Garcia LR
Martins D
Queiroz DAR
Tonon CR
Balin PDS
Polegato BF
Paiva SAR
Azevedo PS
Minicucci M
Zornoff L
Source :
Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2022 Oct 20; Vol. 11 (10). Date of Electronic Publication: 2022 Oct 20.
Publication Year :
2022

Abstract

Cardiac remodeling is defined as a group of molecular, cellular, and interstitial changes that manifest clinically as changes in the heart's size, mass, geometry, and function after different injuries. Importantly, remodeling is associated with increased risk of ventricular dysfunction and heart failure. Therefore, strategies to attenuate this process are critical. Reactive oxygen species and oxidative stress play critical roles in remodeling. Importantly, antioxidative dietary compounds potentially have protective properties against remodeling. Therefore, this review evaluates the role of nutrients and food as modulators of cardiac remodeling.

Details

Language :
English
ISSN :
2076-3921
Volume :
11
Issue :
10
Database :
MEDLINE
Journal :
Antioxidants (Basel, Switzerland)
Publication Type :
Academic Journal
Accession number :
36290787
Full Text :
https://doi.org/10.3390/antiox11102064