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Community-Acquired Acinetobacter radioresistens Bacteremia in an Immunocompetent Host.

Authors :
Lazarev A
Hyun J
Sanchez JL
Verda L
Source :
Cureus [Cureus] 2022 Sep 27; Vol. 14 (9), pp. e29650. Date of Electronic Publication: 2022 Sep 27 (Print Publication: 2022).
Publication Year :
2022

Abstract

Acinetobacter species are gram-negative coccobacilli ubiquitous in nature and widely distributed in the environment. Acinetobacter baumannii is a bacteria commonly seen in the hospital setting, responsible for causing a wide range of bloodstream infections, urinary tract infections, secondary meningitis, infective endocarditis, and wound infections, and is the cause of outbreaks mainly due to its antimicrobial resistance patterns. The use of broad-spectrum antibiotic coverage with carbapenems is essential in the hospital setting. Therefore, carbapenem-resistant  Acinetobacter baumannii  (CRAB) poses as a very challenging pathogen.  Acinetobacter radioresistens, a rare species in comparison to the more prevalent  Acinetobacter baumannii , is an underestimated agent in causing nosocomial infections and also is a potential disseminator of resistance genes. It is also resistant to gamma radiation at 4-8 times higher than other Acinetobacter spp . and is the source of the class D OXA-23 carbapenemase that can confer carbapenem resistance. Therefore, immediate and precise identification of A. radioresistens is crucial for the clinical management of multidrug-resistant bacteremia.<br />Competing Interests: The authors have declared that no competing interests exist.<br /> (Copyright © 2022, Lazarev et al.)

Details

Language :
English
ISSN :
2168-8184
Volume :
14
Issue :
9
Database :
MEDLINE
Journal :
Cureus
Publication Type :
Academic Journal
Accession number :
36321031
Full Text :
https://doi.org/10.7759/cureus.29650