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Biomedical Applications of Plant Extract-Synthesized Silver Nanoparticles.

Authors :
Simon S
Sibuyi NRS
Fadaka AO
Meyer S
Josephs J
Onani MO
Meyer M
Madiehe AM
Source :
Biomedicines [Biomedicines] 2022 Nov 02; Vol. 10 (11). Date of Electronic Publication: 2022 Nov 02.
Publication Year :
2022

Abstract

Silver nanoparticles (AgNPs) have attracted a lot of interest directed towards biomedical applications due in part to their outstanding anti-microbial activities. However, there have been many health-impacting concerns about their traditional synthesis methods, i.e., the chemical and physical methods. Chemical methods are commonly used and contribute to the overall toxicity of the AgNPs, while the main disadvantages of physical synthesis include high production costs and high energy consumption. The biological methods provide an economical and biocompatible option as they use microorganisms and natural products in the synthesis of AgNPs with exceptional biological properties. Plant extract-based synthesis has received a lot of attention and has been shown to resolve the limitations associated with chemical and physical methods. AgNPs synthesized using plant extracts provide a safe, cost-effective, and environment-friendly approach that produces biocompatible AgNPs with enhanced properties for use in a wide range of applications. The review focused on the use of plant-synthesized AgNPs in various biomedical applications as anti-microbial, anti-cancer, anti-inflammatory, and drug-delivery agents. The versatility and potential use of green AgNPs in the bio-medicinal sector provides an innovative alternative that can overcome the limitations of traditional systems. Thus proving green nanotechnology to be the future for medicine with continuous progress towards a healthier and safer environment by forming nanomaterials that are low- or non-toxic using a sustainable approach.

Details

Language :
English
ISSN :
2227-9059
Volume :
10
Issue :
11
Database :
MEDLINE
Journal :
Biomedicines
Publication Type :
Academic Journal
Accession number :
36359308
Full Text :
https://doi.org/10.3390/biomedicines10112792