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Characterization of a Carbapenem-Resistant BKC-1-Producing Clinical Isolate Belonging to the Pseudomonas putida Group from Brazil.

Authors :
Alberto-Lei F
Nodari CS
Streling AP
Bessa-Neto FO
Siqueira AV
CayƓ R
Gales AC
Source :
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2022 Dec 20; Vol. 66 (12), pp. e0083922. Date of Electronic Publication: 2022 Nov 15.
Publication Year :
2022

Abstract

Since its first report, the class A Brazilian Klebsiella carbapenemase (BKC) has been detected only among Enterobacterales isolates from Brazilian hospitals. In this study, we characterized a multidrug-resistant Pseudomonas juntendi clinical isolate and identified a 43.3-kb plasmid carrying bla <subscript>BKC-1</subscript> and a class 1 integron (In 1996 ) containing the arr-2 , qnrVC1 , dfrA21 , and aac(6')-Ib' gene cassettes. Our results confirm the ability of Pseudomonas putida group isolates to acquire antimicrobial resistance determinants and further act as resistance reservoirs.

Details

Language :
English
ISSN :
1098-6596
Volume :
66
Issue :
12
Database :
MEDLINE
Journal :
Antimicrobial agents and chemotherapy
Publication Type :
Academic Journal
Accession number :
36377877
Full Text :
https://doi.org/10.1128/aac.00839-22