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Association between Dural AVFs and Cerebral Venous Thrombosis.

Authors :
Kuiper L
Sánchez van Kammen M
Coert BA
Verbaan D
Emmer BJ
Coutinho JM
van den Berg R
Source :
AJNR. American journal of neuroradiology [AJNR Am J Neuroradiol] 2022 Dec; Vol. 43 (12), pp. 1722-1729. Date of Electronic Publication: 2022 Nov 17.
Publication Year :
2022

Abstract

Background and Purpose: Recent reports suggest an association between dural AVFs and cerebral venous thrombosis. We aimed to investigate the specific temporal and anatomic association between the 2 conditions.<br />Materials and Methods: A consecutive cohort of adult patients with dural AVFs was seen at Amsterdam University Medical Centers (2007-2020). An experienced neuroradiologist re-evaluated the presence and imaging characteristics of dural AVFs and cerebral venous thrombosis on all available imaging. The temporal (previous/concurrent/subsequent) and anatomic (same/adjacent/unrelated venous sinus or vein) association between dural AVFs and cerebral venous thrombosis was determined.<br />Results: Among 178 patients with dural AVFs, the mean age was 58.3 (SD, 13.2) years and 85 (48%) were women. Of 55 patients (31%) with cerebral venous thrombosis, 34 (62%) were women. Four patients (7%) had cerebral venous thrombosis before the development of a dural AVF, 33 (60%) had cerebral venous thrombosis at the time of dural AVF diagnosis (concurrent), and 18 (33%) developed cerebral venous thrombosis during follow-up after conservative treatment. The incidence rate of cerebral venous thrombosis after a dural AVF was 79 per 1000 person-years (95% CI, 50-124). In 45 (82%) patients with dural AVFs and cerebral venous thrombosis, the thrombosis was located in the same venous sinus as the dural AVF, whereas in 8 (15%) patients, thrombosis occurred in a venous sinus adjacent to the dural AVF.<br />Conclusions: One-third of patients with a dural AVF in this study were diagnosed with cerebral venous thrombosis. In almost two-thirds of patients, cerebral venous thrombosis was diagnosed prior to or concurrent with the dural AVF. In 97% of patients, there was an anatomic association between the dural AVF and cerebral venous thrombosis. These data support the hypothesis of a bidirectional association between the 2 diseases.<br /> (© 2022 by American Journal of Neuroradiology.)

Details

Language :
English
ISSN :
1936-959X
Volume :
43
Issue :
12
Database :
MEDLINE
Journal :
AJNR. American journal of neuroradiology
Publication Type :
Academic Journal
Accession number :
36396334
Full Text :
https://doi.org/10.3174/ajnr.A7652