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SNH Amidation of 5-Nitroisoquinoline: Access to Nitro- and Nitroso Derivatives of Amides and Ureas on the Basis of Isoquinoline.
- Source :
-
Molecules (Basel, Switzerland) [Molecules] 2022 Nov 14; Vol. 27 (22). Date of Electronic Publication: 2022 Nov 14. - Publication Year :
- 2022
-
Abstract
- For the first time, amides and ureas based on both 5-nitroisoquinoline and 5-nitrosoisoquinoline were obtained by direct nucleophilic substitution of hydrogen in the 5-nitroisoquinoline molecule. In the case of urea and monosubstituted ureas, only 5-nitrosoisoquinoline-6-amine is formed under anhydrous conditions.
- Subjects :
- Amides
Isoquinolines
Urea
Nitroquinolines
Subjects
Details
- Language :
- English
- ISSN :
- 1420-3049
- Volume :
- 27
- Issue :
- 22
- Database :
- MEDLINE
- Journal :
- Molecules (Basel, Switzerland)
- Publication Type :
- Academic Journal
- Accession number :
- 36431962
- Full Text :
- https://doi.org/10.3390/molecules27227862