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Multisite Detection of Tn 1549 -Mediated vanB Vancomycin Resistance in Multidrug-Resistant Enterococcus faecalis ST6 in Texas and Florida.
- Source :
-
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2023 Jan 24; Vol. 67 (1), pp. e0128422. Date of Electronic Publication: 2022 Dec 21. - Publication Year :
- 2023
-
Abstract
- In the United States, vanB -mediated resistance in enterococci is rare. We characterized three sequence type (ST) 6, vancomycin-resistant Enterococcus faecalis isolates causing bacteremia in unique patients in spatiotemporally distinct settings. Isolates were recovered between 2018 and 2020 in two cities in the United States (Houston, TX; Miami, FL). The isolates harbored the vanB operon on a chromosomally located Tn 1549 transposon, and epidemiological data suggested multiple introductions of the vanB gene cluster into ST6 E. faecalis.
- Subjects :
- Humans
Enterococcus faecalis genetics
Vancomycin Resistance genetics
Florida epidemiology
Texas epidemiology
Bacterial Proteins genetics
Anti-Bacterial Agents pharmacology
Enterococcus faecium
Vancomycin-Resistant Enterococci genetics
Gram-Positive Bacterial Infections drug therapy
Gram-Positive Bacterial Infections epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1098-6596
- Volume :
- 67
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Antimicrobial agents and chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 36541772
- Full Text :
- https://doi.org/10.1128/aac.01284-22