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A pig model carrying heterozygous point mutation of NCSTN simulates familial acne inversa and reveals dysregulated cholesterol biosynthesis via the Notch-pAMPK-HMGCR pathway.

Authors :
Song R
Liu K
Wang Y
Qin G
Xiao M
Liu Y
Yang J
Zong R
Yan X
Zheng Q
Zhang H
Hou N
Yao J
Wang X
Wang Y
Zhao J
Zhang X
Source :
Science bulletin [Sci Bull (Beijing)] 2021 Dec 15; Vol. 66 (23), pp. 2343-2346. Date of Electronic Publication: 2021 May 23.
Publication Year :
2021

Abstract

Competing Interests: Conflict of interest The authors declare that they have no conflict of interest.

Details

Language :
English
ISSN :
2095-9281
Volume :
66
Issue :
23
Database :
MEDLINE
Journal :
Science bulletin
Publication Type :
Academic Journal
Accession number :
36654118
Full Text :
https://doi.org/10.1016/j.scib.2021.05.022