Physiologically based pharmacokinetic modeling to predict OAT3-mediated drug-drug interactions of meropenem in varying stages of chronic kidney disease.

Authors :: Dong J
Liu J
Liu Y
Yao J
Lu Y
Jiao Z
Li W
Source :: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2023 Apr 01; Vol. 183, pp. 106395. Date of Electronic Publication: 2023 Jan 28.
Publication Year :: 2023
Abstract: Competing Interests: Declaration of Competing Interest The authors confirm that they do not have any conflicts of interest to declare.

Subjects :: Humans
Meropenem
Drug Interactions
Kidney
HEK293 Cells
Organic Anion Transporters, Sodium-Independent
Renal Insufficiency, Chronic

Language :: English
ISSN :: 1879-0720
Volume :: 183
Database :: MEDLINE
Journal :: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Publication Type :: Academic Journal
Accession number :: 36716979
Full Text :: https://doi.org/10.1016/j.ejps.2023.106395

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