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Eosinophilic Fasciitis: Current and Remaining Challenges.
- Source :
-
International journal of molecular sciences [Int J Mol Sci] 2023 Jan 19; Vol. 24 (3). Date of Electronic Publication: 2023 Jan 19. - Publication Year :
- 2023
-
Abstract
- Eosinophilic fasciitis (EF), defined as diffuse fasciitis with eosinophilia by Shulman in 1974, is a disease with unknown etiology and whose pathogenesis is still being researched. The diagnosis is based on the clinical aspects (skin induration with an "orange peel" appearance), the lab results (eosinophilia, increased inflammatory markers), the skin biopsy with the pathognomonic histopathological result, as well as the typical MRI changes. The treatment includes glucocorticoids and immunosuppressive drugs. Due to severe refractory cases, the treatment remains a challenge. EF is still a disease with potential for further research.
Details
- Language :
- English
- ISSN :
- 1422-0067
- Volume :
- 24
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- International journal of molecular sciences
- Publication Type :
- Academic Journal
- Accession number :
- 36768300
- Full Text :
- https://doi.org/10.3390/ijms24031982