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Real-world treatment patterns and healthcare costs in patients with psoriasis taking systemic oral or biologic therapies.
- Source :
-
The Journal of dermatological treatment [J Dermatolog Treat] 2023 Dec; Vol. 34 (1), pp. 2176708. - Publication Year :
- 2023
-
Abstract
- Background: Psoriasis is a chronic, immune-mediated, systemic inflammatory disorder associated with high costs. This study evaluated real-world treatment patterns and associated costs in patients in the United States with psoriasis initiating systemic oral or biologic treatments.<br />Methods: This retrospective cohort study used IBM <superscript>®</superscript> (now Merative™) MarketScan <superscript>®</superscript> Commercial and Medicare claims (1 January 2006-31 December 2019) to evaluate patterns of switching, discontinuation, and nonswitching in two cohorts of patients initiating oral or biologic systemic therapy. Total pre-switch and post-switch costs were reported per-patient per-month (PPPM).<br />Results: Each cohort was analyzed (oral, n = 11,993; biologic; n = 9753). Among the oral and biologic cohorts, 32% and 15% discontinued index and any systemic treatment within 1 year of initiation; 40% and 62% remained on index therapy; and 28% and 23% switched treatment, respectively. In the oral and biologic cohorts, total PPPM costs within 1 year of initiation for nonswitchers, patients who discontinued, and patients who switched were $2594, $1402, and $3956, respectively, and $5035, $3112, and $5833, respectively.<br />Conclusion: This study identified lower persistence in the oral treatment cohort, higher costs associated with switching, and a need for safe and effective oral treatment options for patients with psoriasis to delay the switch to biologic therapy.
Details
- Language :
- English
- ISSN :
- 1471-1753
- Volume :
- 34
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- The Journal of dermatological treatment
- Publication Type :
- Academic Journal
- Accession number :
- 36794863
- Full Text :
- https://doi.org/10.1080/09546634.2023.2176708