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Presence of alpha-1-antitrypsin on mitogen-stimulated human lymphocytes.

Authors :
Lipsky JJ
Berninger RW
Hyman LR
Talamo RC
Source :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 1979 Jan; Vol. 122 (1), pp. 24-6.
Publication Year :
1979

Abstract

Human lymphocytes that have undergone concanavalin A-induced blastogenetic transformation demonstrate surface alpha-1-antitrypsin by immunofluorescence when examined after 72 hr of culture, whereas unstimulated cells do not. These results may indicate a role for alpha-1-antitrypsin in lymphocyte blastogenesis.

Subjects

Subjects :
Concanavalin A pharmacology
Fluorescent Antibody Technique
Humans
Immune Sera pharmacology
Immunoglobulin Fc Fragments
Receptors, Antigen, B-Cell
Lymphocyte Activation
Lymphocytes immunology
Mitogens pharmacology
alpha 1-Antitrypsin immunology

Details

Language :
English
ISSN :
0022-1767
Volume :
122
Issue :
1
Database :
MEDLINE
Journal :
Journal of immunology (Baltimore, Md. : 1950)
Publication Type :
Academic Journal
Accession number :
368236

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